Has anyone ever used them?

1. Do they work?
2. Are there any side effects? (it states not but they would wouldnt they)
3. Ay other negatives to note?

Every single drug, whether it be aspirin or alcohol or any of the other acne treatments you mentioned, each in effect attack the body to eliminate a specific symptom of disease.

In the case of the the acne medications, they may likely work, to be honest, but you have to understand that all drugs affect the body in a negative way. No drug is really "healthy" or "safe".

My suggestion would be to instead eliminate the root cause of acne instead of trying to address the symptoms that the disease causes.

Read more here: http://www.raw-food-health.net/naturalacnecure.html